Advanced Biomarker Testing:

Lp(a) is a genetic variant of LDL cholesterol that promotes arterial inflammation and blood clotting. Often described as "the most dangerous cholesterol biomarker you've never heard of" in cardiovascular medicine.

• Inherited genetic risk factor for early heart attack, stroke, and cardiovascular disease
• Not significantly influenced by diet or standard exercise interventions (unlike other lipid markers)
• Affects approximately 20% of the population with elevated levels
• Requires specific targeted treatment approaches different from standard cholesterol management

Lp(a) is rarely included in standard cardiovascular assessment, even though elevated levels can triple heart attack risk. Since levels are genetically determined, discovering high Lp(a) allows family members to get tested and implement appropriate preventive strategies.

Insights Helps:
Our advanced AI examines your family cardiovascular history, existing lipid biomarker results, and personal cardiovascular risk factors to determine if Lp(a) testing would provide valuable information for your health profile. If you've already been tested, Sage Healthspan Insights provides clear context about what your specific Lp(a) results mean and appropriate personalized next steps.

Beyond basic TSH testing, a complete thyroid function assessment includes Free T3, Free T4, Reverse T3, and thyroid antibody testing for thorough evaluation.

• Many individuals have "normal" TSH results but abnormal T3 or T4 levels affecting metabolism
• Thyroid antibody testing can identify autoimmune thyroid conditions before TSH levels change
• Reverse T3 testing can reveal stress-induced thyroid hormone resistance
• T3:T4 ratio analysis provides insight into thyroid hormone conversion efficiency

A basic TSH test alone fails to detect early thyroid dysfunction and the root causes of thyroid-related symptoms. Many people suffer with unexplained fatigue, weight management issues, and cognitive problems for years because their complete thyroid function isn't properly assessed.

Our AI analyzes your reported symptoms alongside any existing thyroid biomarker results to identify patterns suggesting the need for comprehensive thyroid assessment. It provides clear visualizations of thyroid hormone relationships and personalized recommendations for achieving optimal thyroid function based on your unique profile.

Beyond basic estradiol or testosterone measurement, includes complete assessment of estrone, estriol, progesterone, DHEA-S, and their metabolites for complete hormonal evaluation.

• Hormone ratios and balance often matter more than absolute hormone levels
• Hormone metabolite testing reveals how your body processes key hormones
• Provides detailed insight into perimenopause/andropause transitions and hormonal shifts
• Helps identify root hormonal causes of specific symptoms for targeted treatment

Basic hormone testing frequently leaves women experiencing perimenopause or men with age-related hormonal changes without clear answers. Comprehensive hormone assessment reveals the subtle hormonal shifts driving symptoms and long-term health risks.

Our sophisticated AI correlates your age, reported symptoms, and any existing hormone test results to identify which additional hormone biomarkers would provide the most valuable information for your specific situation. It also analyzes complex hormone relationships and provides evidence-based insights about optimizing your hormonal health and balance.

A direct measure of insulin levels after fasting, revealing how intensively your pancreas must work to maintain normal glucose levels and metabolic function.

• Fasting insulin rises years before blood glucose becomes abnormal
• Directly linked to metabolic syndrome development and type 2 diabetes risk
• Strong predictor of future weight management challenges and metabolic efficiency
• Associated with systemic inflammation and increased cardiovascular risk

Fasting glucose or HbA1c testing alone fail to detect the earliest signs of metabolic dysfunction. Many individuals have "normal" glucose readings but significantly elevated insulin levels, indicating metabolic problems years before standard testing would identify them.

Our AI examines your glucose history, lipid patterns, weight trends, and related markers to identify early signs of insulin resistance. It provides personalized recommendations for metabolic optimization based on your unique pattern of biomarker results and health history.

Homeostatic Model Assessment of Insulin Resistance—a calculated value using glucose and insulin measurements that precisely quantifies insulin resistance and metabolic function.

• Quantifies insulin resistance before glucose abnormalities develop
• Helps distinguish between different types of metabolic dysfunction
• Provides an objective baseline to measure intervention effectiveness
• Strongly linked to future cardiometabolic disease risk

Without directly measuring insulin resistance, healthcare providers often dismiss early metabolic warning signs. HOMA-IR calculation reveals metabolic problems while they're still reversible through targeted lifestyle interventions.

When you have both glucose and insulin test results available, our AI automatically calculates your HOMA-IR value and tracks it longitudinally over time. It analyzes trends in this critical metabolic marker and provides actionable steps for improving insulin sensitivity based on evidence-based interventions.

A sensitive marker of systemic inflammation that indicates increased cardiovascular risk and inflammatory burden.

• Independent predictor of heart attack, stroke, and cardiovascular event risk
• Helps identify hidden inflammatory processes before symptoms develop
• Guides intensity of preventive health strategies based on risk level
• Monitors effectiveness of anti-inflammatory lifestyle interventions

Standard medical assessment often ignores inflammatory status until disease manifests clinically. Tracking hs-CRP reveals whether your lifestyle modifications are actually reducing your inflammatory burden and disease risk.

Our AI correlates your hs-CRP results with other inflammatory biomarkers and health conditions to provide context about your specific inflammatory status. It identifies patterns suggesting specific causes of inflammation and tracks the effectiveness of your anti-inflammatory interventions longitudinally.

The active circulating form of Vitamin D that accurately indicates your body's true vitamin D status and sufficiency.

• Essential for immune regulation, bone metabolism, and mood stabilization
• Deficiency linked to numerous chronic diseases and health conditions
• Optimal levels differ significantly from conventional "normal" reference ranges
• Difficult to achieve optimal levels without testing and personalized supplementation

Vitamin D is tested inconsistently and often evaluated using outdated reference ranges. Optimal levels for disease prevention are typically higher than standard "normal" laboratory ranges suggest.

Our AI tracks your Vitamin D levels longitudinally and in relation to seasonal variations. It provides personalized recommendations for reaching and maintaining optimal vitamin D levels based on your specific test results, geographical latitude, skin pigmentation, age, and other relevant factors.

Measures the percentage of EPA and DHA (essential omega-3 fatty acids) incorporated in red blood cell membranes, reflecting tissue levels.

• Directly linked to cardiovascular health outcomes and disease risk
• Associated with cognitive function, neurological health, and brain aging
• More accurate than dietary questionnaires for assessing true omega-3 status
• Helps determine personalized optimal supplementation strategies

Despite strong scientific evidence linking omega-3 status to health outcomes, this test is rarely included in standard medical assessments. Many people supplementing with fish oil have no objective way to know if they're reaching therapeutic tissue levels.

For those who have completed omega-3 index testing, our AI provides context for your specific results and tracks changes in response to dietary modifications or supplementation protocols. It also analyzes your personal risk factors to determine if this specialized testing would be particularly valuable in your comprehensive health monitoring.