The Male Comprehensive Panel is ideal for:
The Female Comprehensive Panel offers an in-depth look at essential health markers that can help identify early signs of chronic conditions and provide insight into your overall well-being. This panel covers key areas such as metabolic health, cardiovascular health, and hormone levels. This level of comprehensive testing is not always easy to obtain, as many doctors might only check these markers when health issues have already progressed. By being proactive with this panel, you and your healthcare provider can monitor critical health indicators and address potential concerns before they become more serious, giving you greater control over your long-term wellness.
We recommend completing the Female Comprehensive Panel at least yearly, if not every 6 months, to maintain a complete overview of your health and catch any potential issues early.
Globulin is a group of proteins in the blood that play essential roles in fighting infections, forming blood clots, and supporting liver and kidney functions. Abnormal globulin levels can indicate various health issues, so addressing them depends on the underlying cause.
Testing globulin levels helps assess if you have the right amount to maintain health, fight infections, and transport nutrients effectively.
Low Globulin Levels (Hypoglobulinemia) - Causes
Low globulin levels can indicate gastrointestinal or liver dysfunction, renal disease, various cancers, immune deficiencies, malnutrition, severe burns, or trauma.
High Globulin Levels (Hyperglobulinemia) - Causes
Increased levels may be due to autoimmune diseases, chronic infections or inflammatory diseases, certain cancers, or liver diseases. Dehydration or pregnancy can cause temporary increases.
Abnormal Globulin Levels - Symptoms
Symptoms of abnormal globulin levels are often related to the underlying cause. Symptoms can include:
Glucose is a type of sugar derived from food and the body's primary energy source. It is transported through the bloodstream to various tissues. Your liver stores extra glucose which is utilized during times when you are not eating.
Blood glucose levels are measured to assess how effectively the body processes and utilizes this important energy source.
Low Glucose (Hypoglycemia) may be caused by:
Low Glucose (Hypoglycemia) - Acute Symptoms:
Low Glucose (Hypoglycemia) - Severe Symptoms:
High Serum Glucose (Hyperglycemia): Too much glucose in the blood can be a sign of diabetes, a serious medical condition that can cause tissue and organ damage if it is not managed. Causes include:
High Serum Glucose (Hyperglycemia) - Acute Symptoms
High Serum Glucose (Hyperglycemia) - Chronic Symptoms
Hemoglobin A1C (HbA1c) is a blood test measuring the average blood glucose (sugar) level over the past two to three months. It reflects the percentage of hemoglobin, a protein in red blood cells, that is coated with sugar (glycated). The HbA1c test is commonly used to diagnose and monitor diabetes and assess how well blood sugar levels are managed over time.
Low HbA1c Levels (<4.0%) - Causes
Low HbA1c Levels (<4.0%) - Symptoms
High HbA1c Levels (≥6.5%) - Causes
High HbA1c Levels (≥6.5%) - Symptoms
Insulin is a hormone produced by the pancreas that plays a key role in regulating blood sugar (glucose) levels. Its primary function is to maintain stable blood sugar levels by facilitating uptake of glucose into cells, especially in response to meals.
Understanding your fasting insulin levels can provide important insights into your metabolic health. If your levels are outside the normal range, it’s crucial to consult with a healthcare provider to determine the underlying cause and appropriate treatment.
Clinical Uses for the Insulin Test
When to Test Insulin Levels
Low Insulin Levels - Causes
Low Insulin Levels - Symptoms
High Insulin Levels - Causes
High Insulin Levels - Symptoms
Sodium is an important electrolyte that helps keep the right balance of fluids in your body. It also ensures that your muscles and nerves work properly.
A sodium test measures the sodium in your blood, revealing much about your health. It can show whether you drink enough water or your kidneys and heart are functioning well. Measuring sodium levels is important for diagnosing and treating several health conditions.
Low Sodium Levels (Hyponatremia) - Causes
Low Sodium Levels - Symptoms
High Sodium Levels (Hypernatremia) - Causes
High Sodium Levels - Symptoms
Arachidonic acid (AA) is an Omega-6 polyunsaturated fatty acid found in certain foods that plays a key role in the inflammatory response and cellular signaling. It's a component of cell membranes and serves as a precursor for various signaling molecules, including those involved in inflammation and immune responses. While AA is essential for bodily functions, imbalances can lead to health issues.
Low AA Levels - Causes
Low AA Levels - Signs & Symptoms
High AA Levels - Causes
High AA Levels - Signs & Symptoms
The Arachidonic Acid/EPA Ratio is a measure that compares the levels of arachidonic acid (AA), an omega-6 fatty acid, to eicosapentaenoic acid (EPA), an omega-3 fatty acid, in the body. Arachidonic acid is involved in inflammation, while EPA has anti-inflammatory properties. The ratio helps assess inflammation levels and overall cardiovascular health.
Low Ratio - Causes: A lower ratio may suggest a stronger anti-inflammatory profile, often seen in individuals with high omega-3 intake. A low ratio is usually caused by a diet rich in omega-3, fish oil supplementation, or low levels of dietary omega-6 fats.
Low Ratio - Symptoms: A low ratio may cause few symptoms but could indicate appropriate inflammatory responses and heart health.
High Ratio - Causes: This often indicates a higher level of inflammation, as arachidonic acid is associated with pro-inflammatory processes. A high ratio is usually caused by a diet high in omega-6 fats (such as processed foods and vegetable oils), a low intake of omega-3 (like fatty fish 9 or fish oil supplements), or chronic inflammatory conditions.
High Ratio - Symptoms
Docosahexaenoic Acid (DHA) is a long-chain omega-3 fatty acid that is a critical component of the brain, eyes, and other tissues throughout the body. DHA plays a key role in brain development and function, especially in infants and young children. It is also important for maintaining heart health, reducing inflammation, and supporting overall well-being.
The DHA (Docosahexaenoic Acid) test measures the level of DHA in the blood. This test is often part of a broader fatty acid profile or Omega-3 Index, which assesses the balance of omega-3 and omega-6 fatty acids in the body. The test is used to assess cognitive health, cardiovascular health, prenatal and infant health as well as inflammation and nutritional balance.
Low DHA Levels - Causes
Low Levels - Symptoms
High DHA Levels - Causes
High DHA Levels - Symptoms
Docosapentaenoic Acid (DPA) is a long-chain omega-3 fatty acid found in fish oil, marine sources, and to some extent in the human body. DPA is often considered a beneficial nutrient, playing a role in various physiological processes, such as:
Low Levels of DPA - Causes
Low Levels of DPA - Symptoms
High Levels of DPA - Causes
High Levels of DPA - Symptoms
There are typically no direct symptoms of high DPA levels, as it is generally considered beneficial. However, excessive omega-3 intake can potentially lead to issues such as excessive bleeding, as omega-3s can thin the blood.
Eicosapentaenoic Acid (EPA) is an omega-3 polyunsaturated fatty acid primarily found in cold-water fish like salmon, mackerel, and sardines. EPA plays a crucial role in reducing inflammation, supporting heart health, and regulating mood. It is often associated with its benefits in lowering the risk of cardiovascular disease, reducing triglycerides, and supporting mental health.
While optimal EPA levels may vary among individuals, some studies suggest that higher levels of EPA in the blood are associated with greater cardiovascular protection.
Low EPA Levels - Causes
Low EPA Levels - Signs & Symptoms
High EPA Levels - Causes
High EPA Levels - Signs & Symptoms
Cholesterol is a waxy, fat-like substance found in all the cells in your body. Often referred to as "bad cholesterol," LDL cholesterol is a type of lipoprotein that carries cholesterol from the liver to the cells throughout the body. When present in excess, LDL cholesterol can deposit in the walls of arteries, leading to plaque formation, which narrows the arteries and increases the risk of cardiovascular diseases like heart attacks and strokes.
Your liver makes cholesterol and it's also in some foods, such as meat and dairy products. Your body needs some cholesterol to work properly. However, having too much cholesterol in your blood raises your risk of coronary artery disease (CAD).
The Low-Density Lipoprotein (LDL) Cholesterol Test measures the amount of LDL cholesterol in the blood and is part of a routine lipid panel. It is used to evaluate the risk of developing heart disease and to monitor the effectiveness of LDL-lowering protocols.
Low LDL - Causes & Symptoms
Low LDL cholesterol levels are generally considered very healthy and do not cause noticeable symptoms. Genetic disorders, malnutrition, hyperthyroidism, liver disease, or medication may cause low levels. Very low levels might be associated with:
Causes
Symptoms
Medium Low-Density Lipoprotein Particles (Medium LDL-P) are cholesterol particles that transport fats from your liver to other parts of your body, where they help create cells and make certain hormones.
This test quantifies Medium LDL-P levels and provides insight into cholesterol management and CVD risk.
Low Medium LDL-P Levels might mean your body isn't making or moving around as much cholesterol as it usually does. Low levels are uncommon but may indicate an efficient cholesterol metabolism or underlying health conditions.
There are generally no symptoms of low Medium LDL-P levels. However, in some cases, individuals might experience fatigue, unexplained weight loss, or issues related to hormonal imbalances. Regular monitoring and working with healthcare providers are crucial for managing LDL-P levels.
Low Medium LDL-P - Causes
High Medium LDL-P can increase the risk of cardiovascular disease (CVD) by 1.2 to 1.4 times. While there are no symptoms associated with elevated levels, over time, elevated levels could contribute to the development of atherosclerosis, which may lead to symptoms such as chest pain or discomfort, shortness of breath, or fatigue during physical activity.
High Medium LDL-P - Causes
Low-Density Lipoprotein particles (LDL-P) are a key component of LDL cholesterol, responsible for transporting fats through the bloodstream. When these particles become trapped in the artery walls, they contribute to the buildup of fatty plaques, which can increase the risk of heart attacks or strokes.
The higher the concentration of LDL-P in the blood, the greater the likelihood of plaque formation. Studies indicate that elevated LDL-P levels can raise cardiovascular risk, even when total cholesterol and LDL-C levels appear normal. This helps explain why some individuals experience heart attacks despite not having high total cholesterol or LDL-C.
While standard LDL-C tests are helpful for assessing cardiovascular disease (CVD) risk, they may not fully capture the risk for some individuals, particularly those with conditions like diabetes. In such cases, LDL-P testing can provide a more accurate picture of cardiovascular risk, offering valuable insight for those with normal LDL-C levels but elevated risk factors.
Low LDL Particle Numbers - Causes
Low LDL Particle Numbers - Symptoms
High LDL Particle Numbers - Causes
High LDL Particle Numbers - Symptoms
LDL cholesterol is often referred to as 'bad' cholesterol. There are different types of LDL particles: small, dense LDL, and large, buoyant LDL. The size and density of LDL particles can provide more detailed information about cardiovascular risk than just measuring total LDL cholesterol.
The LDL Pattern test categorizes LDL particles into the following types based on their size and density.
Abnormal LDL Pattern - Causes
Abnormal LDL Pattern - Symptoms
The size of LDL particles can provide more detailed information about cardiovascular risk beyond just measuring total LDL cholesterol. Larger LDL particles are generally considered less atherogenic (less likely to promote the formation of plaque in the arteries) than smaller, denser LDL particles.
The LDL (Low-Density Lipoprotein) peak size test measures the average size of LDL particles in your blood.
Abnormal LDL Peak Size - Causes
Abnormal LDL Peak Size - Symptoms
Sex Hormone Binding Globulin (SHBG) is a glycoprotein produced mainly in the liver that binds to sex hormones, specifically testosterone and estrogen, in the bloodstream. SHBG controls the amount of testosterone and estrogen that is available for the body's tissues to use. When hormones are bound to SHBG, they are inactive and cannot be used by cells. The levels of SHBG can influence the balance of available sex hormones, affecting many bodily processes.
The Sex Hormone Binding Globulin (SHBG) test measures the level of SHBG in your blood. This test is often used to help diagnose conditions related to abnormal levels of sex hormones, such as testosterone and estrogen. It is particularly useful when total hormone levels are normal, but symptoms of hormone imbalance are present.
Low SHBG levels have been associated with an increased risk of developing type 2 diabetes, cardiovascular disease, and metabolic disorders including metabolic syndrome, as well as some cancers and arthritis in both genders.
Low SHBG - Causes
Low SHBG - Symptoms
Often, higher levels of SHBG are associated with positive health outcomes. For example, elevated SHBG levels have been linked to a lower risk of type 2 diabetes and prostate cancer. However, they are also linked to a higher risk of bone loss and fractures, hypogonadism in males, and hepatic cirrhosis. In some cases, it may be caused by hyperthyroidism, as thyroid hormone stimulates the production and release of SHBG.
High SHBG - Causes
High SHBG - Symptoms
Testosterone is a key male sex hormone and an androgenic steroid. It's essential for both men and women, influencing libido, muscle mass, bone density, red blood cell production, mood, and overall well-being. In men, it also drives the development of masculine characteristics such as deeper voice, facial and body hair, and a more muscular body shape.
A total testosterone test measures the hormone's total amount in the blood, aiding in the evaluation of sexual dysfunction, infertility, and endocrine disorders. The total testosterone test measures two forms of testosterone, bound and free. Both of these forms decline with age.
Low Testosterone in Men
Low Testosterone in Women
High Testosterone in Men - Physical Symptoms
High Testosterone in Men - Behavioral Symptoms
High Testosterone in Men - Other Symptoms
High Testosterone in Women
Free Testosterone is the portion of testosterone that is not bound to proteins in the blood, making it biologically active and available to interact with cells and tissues. While most testosterone in the blood is bound to sex hormone-binding globulin (SHBG) or albumin, only a small fraction is "free" and active, which plays a crucial role in various bodily functions.
The Free Testosterone test measures the amount of unbound testosterone in the bloodstream. This test is often used when total testosterone levels are borderline or do not match clinical symptoms. It's beneficial in evaluating conditions related to hormone imbalance, such as hypogonadism in men or polycystic ovary syndrome (PCOS) in women.
Causes
Symptoms
Causes
Symptoms
MCHC (Mean Corpuscular Hemoglobin Concentration) measures the average hemoglobin concentration in a given volume of red blood cells. Hemoglobin is a protein carried by RBC that plays a vital role in supporting overall health. It delivers oxygen to organs and tissues throughout the body. It also transports carbon dioxide back to the lungs where it can be exhaled.
MCHC is generally not interpreted separately from other blood values. To be a meaningful diagnostic test, it must be compared with RBC indices and measurements on a CBC to diagnose anemia and determine the underlying cause.
Low MCHC (Hypochromic Anemia)- Causes
Low MCHC - Symptoms
Low MCHC - Progressing Symptoms
High MCHC Levels (Hyperchromic Anemia) - Causes
High MCHC Levels - Symptoms
MCV (mean corpuscular volume) measures the average size of your red blood cells. It's included in a common blood test called a complete blood count (CBC). Considered alongside the results of other tests, an MCV blood test can provide insights into how your red blood cells are functioning, helping your healthcare provider determine if you have anemia, liver disease, or other conditions.
Low MCV (Microcytosis) - Causes
Low MCV - Symptoms
High MCV (Macrocytosis) - Causes
High MCV - Symptoms
Monocytes are a type of white blood cell that serves as a crucial component of your immune system. They play a vital role in fighting infections, removing dead or damaged tissues, and regulating immune responses.
The monocyte test reflects the monocyte count as a percentage of all the white blood cells.
Low Monocytes (Monocytopenia) - Causes
Low Monocytes - Symptoms
High Monocytes (Monocytosis) - Causes
High Monocytes - Symptoms
Neutrophils are the most common type of white blood cell. Like security guards, they patrol the bloodstream and act like the immune system's first responders whenever an infection or injury occurs. They are always ready to fight off invaders like bacteria and fungi, engulfing the pathogen or releasing chemicals to neutralize or eliminate threats to keep you healthy.
When you’re sick or injured, doctors often measure your neutrophil count with a complete blood count (CBC) test to see how your body is responding. This test measures the percentage of neutrophils, a type of white blood cell, in your blood. It's often part of a complete blood count (CBC) and helps detect infections, inflammation, and other health conditions by showing the proportion of neutrophils compared to other white blood cells.
Low Neutrophil Levels (Neutropenia)
Neutropenia is the result of your body destroying neutrophils before your bone marrow can create more.
Causes of a low neutrophil count include infections (hepatitis, tuberculosis, sepsis, Lyme disease, chemotherapy, leukemia, vitamin deficiencies (vitamin B12, folate, copper), or autoimmune disease (Crohn's disease, lupus, rheumatoid arthritis).
Neutropenia does not cause any specific symptoms.
High Neutrophil Levels (Neutrophilia)
In many cases, it's normal for your body to temporarily produce more neutrophils to help you heal, especially with a bone fracture, injury, severe burn, or surgery. However, neutrophils also increase due to infections, inflammation, certain types of leukemia, stress, or reactions to certain drugs. When the number of neutrophils doesn't return to normal after repairing an injury, it can pose a health risk.
Neutrophilia does not cause any specific symptoms.
Red blood cells carry oxygen from your lungs to the rest of your body and take carbon dioxide back to your lungs to be exhaled. This test measures the number of red blood cells in your blood. The RBC count is a key indicator of your overall blood health and can help diagnose various conditions, including anemia or polycythemia.
Elevated RBCs (erythrocytosis or polycythemia): Increased red blood cell (RBC) mass is reflected in elevated hemoglobin and hematocrit levels. Erythrocytosis is associated with an increased risk of thrombotic events due to blood hyperviscosity and can potentially progress to leukemia.
Causes
A low red blood cell count typically indicates iron deficiency anemia, but may be caused by the following:
Symptoms
Causes
Symptoms