Female Comprehensive Panel

$499

The Male Comprehensive Panel is ideal for:

Anyone who hasn’t had a comprehensive health panel done recently, providing a crucial baseline for tracking health over time.
Men who want a broad and detailed look at their health markers.
Individuals who are managing chronic health conditions and need a clear picture of how their body is responding.
Those focused on proactive health management and optimization.
Individuals who may have a family history of chronic conditions, or simply want to understand their body better.

Female Comprehensive Panel

The Female Comprehensive Panel offers an in-depth look at essential health markers that can help identify early signs of chronic conditions and provide insight into your overall well-being. This panel covers key areas such as metabolic health, cardiovascular health, and hormone levels. This level of comprehensive testing is not always easy to obtain, as many doctors might only check these markers when health issues have already progressed. By being proactive with this panel, you and your healthcare provider can monitor critical health indicators and address potential concerns before they become more serious, giving you greater control over your long-term wellness.

How Often You Should Get It Done

We recommend completing the Female Comprehensive Panel at least yearly, if not every 6 months, to maintain a complete overview of your health and catch any potential issues early.

Full List of Tests in Panel

Nutrition / Metabolism

Alanine Aminotransferase (ALT) is an enzyme primarily found in the liver, with smaller amounts in the kidneys, heart, and muscles. It plays a vital role in breaking down proteins and converting them into energy. ALT is released into the bloodstream when the liver is damaged or inflamed. Clinically, ALT is a key biomarker for liver health, as elevated levels often indicate liver injury or disease. Understanding ALT levels helps clinicians diagnose liver disorders, monitor disease progression, and guide treatment decisions.

ALT measurements are useful in diagnosing and managing liver diseases such as viral hepatitis and cirrhosis. ALT activity is generally lower than aspartate aminotransferase (AST) activity and is highest in the liver. Significant ALT elevations occur mainly in liver diseases. ALT is often measured with AST to determine if AST's source is the liver or heart. A normal ALT with elevated AST suggests cardiac disease, while slight ALT elevations can occur with extensive heart muscle damage.

Abnormal ALT Levels

Low ALT: Low ALT levels can result from chronic liver disease, malnutrition, advanced liver cirrhosis, severe vitamin B6 deficiency, or genetic disorders affecting ALT production. Although low ALT levels are less common, they can indicate significant liver damage and require further evaluation.

Symptoms of Low ALT Levels are less common and generally less concerning but can include:

Muscle weakness
Fatigue
Generalized symptoms: Symptoms related to the underlying condition causing low ALT levels.

High ALT: High ALT levels typically signal liver damage or injury, either acute or chronic. Common causes include hepatitis, fatty liver disease, and cirrhosis. Other causes include certain medications (statins, antibiotics, and OTC pain relievers), excessive alcohol consumption, obesity, metabolic disorders like diabetes, and toxin exposure.

ALT levels may also rise temporarily after strenuous exercise or muscle injury, though elevations are more specific to liver injury.

Identifying the cause of elevated ALT is crucial for proper management and treatment, including ruling out drug, alcohol, medication use, and toxin exposure.

Symptoms of Elevated ALT Levels often indicate liver damage or inflammation and can include:

Fatigue: Persistent tiredness and lack of energy
Abdominal discomfort or pain: Especially in the upper right side of the abdomen.
Jaundice: Yellowing of the skin and eyes, indicating bilirubin buildup.
Dark urine: Darker than usual due to bilirubin in the urine.
Pale stools: Stools may be lighter in color, indicating issues with bile production.
Nausea and vomiting: Feeling sick to the stomach or vomiting.
Loss of appetite: Decreased desire to eat, sometimes leading to weight loss.
Swelling: Swelling in the abdomen or legs due to fluid buildup (ascites or edema).
Itchy skin: Generalized itching without an apparent cause.
Bruising or bleeding: Increased tendency to bruise or bleed easily.

Alkaline phosphatase (ALP) is an enzyme found in various tissues, especially the liver, bile duct, bones, kidneys, and digestive system. It plays a role in the breakdown of proteins and is important for liver, bile duct, and bone health.

The ALP Test is used to help diagnose and monitor liver and bone disorders and assess treatment efficacy. Elevated levels may indicate liver or bone diseases, while decreased levels can suggest malnutrition or genetic conditions.

Abnormal Alkaline Phosphatase (ALP) Levels

Low ALP Levels - Causes

Nutritional deficiencies: zinc or magnesium
Malnutrition or malabsorption: including protein deficiency and celiac disease
Rare genetic conditions: Hypophosphatasia or Wilson's Disease
Hypothyroidism (underactive thyroid)
Medications: including oral contraceptives, hormone replacement therapy)

Low ALP Levels - Symptoms

Low ALP levels do not usually cause symptoms but may indicate underlying conditions, such as:

Fatigue
Bone pain or weakness
Delayed growth in children
Muscle weakness
Numbness or tingling
Seizures (in severe cases)

High ALP Levels - Causes

High ALP levels are generally due to underlying conditions, such as:

Liver diseases: hepatitis, cirrhosis, liver cancer
Biliary obstruction: bile duct obstruction, gallstones
Bone disorders: Paget's disease, bone metastasis, hyperparathyroidism, healing fractures
Other: congestive heart failure, pregnancy, adolescent bone growth
GI Issues: Ulcerative colitis or regional enteritis
Autoimmune liver diseases: primary biliary cirrhosis
Certain cancers: Hodgkin's disease, lymphoma, infiltrative diseases

(sarcoidosis), granulomatous disorders.

Medications: Oral contraceptives, antihypertensives.
Lifestyle factors: Excessive alcohol, obesity, or sedentary lifestyle intake can cause liver damage, raising ALP.

High ALP Levels - Symptoms

High (ALP) may not cause specific symptoms directly. However, the underlying conditions can cause various symptoms, depending on the cause.

Liver disease
Jaundice: Yellowing of the skin and eyes.
Abdominal pain: Particularly in the upper right side.
Fatigue: Persistent tiredness or weakness.
Itching: Generalized itching without a rash.
Bone Disorders
Bone pain: Particularly in the hips, spine, or legs.
Bone deformities: Abnormal bone growth or shape.
Increased fractures: Bones may break more easily.
Swelling or tenderness: In affected bones.
Gallbladder Issues
Abdominal pain: Especially after eating fatty foods.
Nausea or vomiting: Often after meals.
Fever: In cases of infection (cholecystitis).
Other Symptoms
Weakness: General weakness and malaise.
Loss of appetite: Especially with liver-related issues.

Omega

Docosahexaenoic Acid (DHA) is a long-chain omega-3 fatty acid that is a critical component of the brain, eyes, and other tissues throughout the body. DHA plays a key role in brain development and function, especially in infants and young children. It is also important for maintaining heart health, reducing inflammation, and supporting overall well-being.

The DHA (Docosahexaenoic Acid) test measures the level of DHA in the blood. This test is often part of a broader fatty acid profile or Omega-3 Index, which assesses the balance of omega-3 and omega-6 fatty acids in the body. The test is used to assess cognitive health, cardiovascular health, prenatal and infant health as well as inflammation and nutritional balance.

Abnormal DHA Levels

Low DHA Levels - Causes

Dietary deficiency: Insufficient intake of DHA-rich foods, such as fatty fish (herring, mackerel, salmon, sardines, or trout), fish oil, walnuts, or fortified foods.
Malabsorption disorders: Conditions like Crohn's disease, celiac disease, or other gastrointestinal issues that impair fat absorption can lead to low DHA levels.
Age: Older adults may have reduced DHA levels due to decreased dietary intake or low conversion from ALA.
Pregnancy and lactation: During pregnancy and breastfeeding, DHA demand increases, and low levels can affect both mother and child.
Lifestyle factors: Stress or heavy drinking could also make it harder for your body to use DHA properly.

Low Levels - Symptoms

Cognitive impairment: Difficulty with memory, focus, and overall cognitive function.
Mood disorders: Increased risk of depression, anxiety, and other mood-related issues.
Poor visual function: Impaired vision, particularly in infants and children.
Developmental delays: Low DHA can lead to delays in learning and behavioral problems in children.
Increased inflammation: Higher susceptibility to inflammatory conditions, such as arthritis or cardiovascular disease.
Dry skin and hair: Reduced skin elasticity and hair quality.

High DHA Levels - Causes

Excessive supplementation: Overconsumption of DHA supplements can lead to abnormally high levels.
A diet rich in DHA: Consuming a large amount of DHA-rich foods (herring, mackerel, salmon, or sardines) or supplements can elevate levels, though this is generally uncommon.
Certain medications: Some medications, like those used for lowering triglycerides, could also contribute to higher DHA levels. Also, high DHA may impact the efficacy of certain medications.

High DHA Levels - Symptoms

Uncommon symptoms: Symptoms of high levels of DHA are generally uncommon, but in some cases, they could include a fishy aftertaste, bad breath, heartburn, nausea, or diarrhea.
Bleeding issues: Excessively high levels can increase the risk of bleeding, particularly in individuals taking blood-thinning medications.
Gastrointestinal issues: Some people may experience nausea, diarrhea, or other digestive problems with high DHA intake.

Cardiovascular Health

Apo B, or apolipoprotein B, is a protein that carries cholesterol from the liver to cells throughout the body. However, it only transports lipids with negative health effects; low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), and others. It does not transport good cholesterol, high-density lipoproteins (HDL).

High levels of ApoB indicate an increased number of atherogenic particles, which can contribute to the buildup of plaque in the arteries, leading to cardiovascular diseases (CVD) such as heart attacks and strokes. As such, Apo B is considered to be a powerful indicator of coronary artery disease (CAD). In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol.

The Apo B or Apolipoprotein B-100 test is a blood test that can tell you about your risk for cardiovascular (heart and blood vessel) disease. Some healthcare providers believe an Apo B test is more accurate than a lipid panel (which measures all those cholesterol types) to estimate cardiovascular disease risk.

Abnormal Apolipoprotein B Levels

Low ApoB Levels - Causes

Genetic factors: Conditions like familial hypobetalipoproteinemia, an inherited disorder that results in abnormally low ApoB levels.
Malabsorption syndromes: Such as celiac disease or chronic pancreatitis, can reduce ApoB levels.
Severe malnutrition: Inadequate intake of calories and essential nutrients can lead to low ApoB levels.
Hyperthyroidism: Overactive thyroid function can lower lipid levels, including ApoB.
Liver disease: Certain liver conditions that impair lipid production can result in low ApoB levels.
Certain medications: Drugs like statins or fibrates, which lower cholesterol levels, may also reduce ApoB levels.

Low ApoB Levels - Symptoms

Often asymptomatic: There may be no direct symptoms.
Potential fat malabsorption symptoms: If related to malabsorption, symptoms may include diarrhea, weight loss, and deficiencies in fat-soluble vitamins (A, D, E, and K).
Possible neurological symptoms: Severe reductions in ApoB, particularly related to genetic disorders, may lead to neurological issues, including peripheral neuropathy.

High ApoB Levels - Causes

Genetic factors: Familial hypercholesterolemia and other inherited lipid disorders.
Diet: High intake of saturated fats, trans fats, and cholesterol.
Obesity: Being overweight or obese is associated with higher ApoB levels.
Metabolic syndrome: A cluster of conditions including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels can raise ApoB.
Diabetes: Poorly controlled diabetes can lead to elevated ApoB.
Hypothyroidism: Underactive thyroid function.
Kidney disease: Certain kidney conditions can result in abnormal lipid metabolism, increasing ApoB.
Certain medications: Some drugs, such as corticosteroids, can increase lipid levels, including ApoB.

High ApoB Levels - Symptoms

Often asymptomatic: There may be no direct symptoms.
Cardiovascular symptoms: If high ApoB contributes to atherosclerosis (the buildup of plaque in the arteries), symptoms may include chest pain (angina), shortness of breath, heart attack, or stroke.

Large HDL (High-Density Lipoprotein) refers to a subtype of HDL cholesterol, often categorized based on particle size. HDL is known as 'good cholesterol' because it helps remove other forms of cholesterol from the bloodstream, transporting it to the liver for excretion.

The classification into 'large' HDL is based on the size of these particles. Large HDL molecules can transport greater quantities of bad cholesterol to the liver, making them more beneficial to cardiovascular health. In contrast, smaller particles do not provide added cardiovascular protection.

This test helps assess cardiovascular disease (CVD) risk in patients with intermediate or high risk based on traditional or emerging risk factors, including:

Existing health conditions: diabetes, high blood pressure, or atherosclerosis
A family history of heart disease
Smoking
Age: Men >45 and women >55 years of age

This test is also used to assess a patient's response to lipid-lowering therapy.

Abnormal Large HDL Particle Levels

Low Large HDL Particle Levels - Causes

Low levels may increase the risk of cardiovascular disease, as there is less HDL available to remove cholesterol from the arteries.

Diet: High intake of trans fats and refined sugars or carbohydrates can lower HDL levels.
Sedentary lifestyle: Lack of physical activity can reduce the levels of large HDL particles.
Obesity: Excess body weight can lower HDL levels, especially large HDL particles.
Type 2 diabetes, and metabolic syndrome: These conditions can reduce the size and number of HDL particles.
Smoking: Smoking is associated with lower HDL levels, including large HDL particles.
Genetics: Some individuals have naturally lower HDL levels.
Certain medications: Some medications, like beta-blockers or anabolic steroids, can lower HDL levels.
Type 2 diabetes, and metabolic syndrome: These conditions can reduce the size and number of HDL particles.

Low Large HDL Particle Levels - Symptoms

Generally asymptomatic
Low levels are associated with an increased risk of cardiovascular disease. Symptoms related to cardiovascular issues might include chest pain, shortness of breath, or fatigue.

Elevated Large HDL Particle Levels - Causes

Elevated levels are typically not a cause for concern. While having high HDL levels is generally considered beneficial, excessively high levels may be associated with certain health issues.

Genetics: Some individuals naturally have higher HDL levels.
Medications: Certain drugs, such as niacin and fibrates, can elevate HDL.
Estrogen: Hormone replacement therapy or higher estrogen levels in women can increase HDL, particularly large HDL particles.

Elevated Large HDL Particle Levels - Symptoms

Generally asymptomatic
Considered protective against cardiovascular disease.

C-reactive protein (CRP) is a substance the liver produces in response to inflammation. The High-Sensitivity C-Reactive Protein (hs-CRP) Test is a more precise version of the standard CRP test. It is designed to measure very low levels of CRP in the blood, which can indicate low-grade inflammation.

The hs-CRP test is primarily used to assess the risk of cardiovascular diseases, such as heart attack and stroke. Since low-grade inflammation plays a role in the development of atherosclerosis (the buildup of plaque in the arteries), measuring hs-CRP levels can help identify individuals at higher risk for these conditions, even if they appear otherwise healthy. It is also used to help monitor chronic inflammatory conditions such as rheumatoid arthritis, lupus, or other autoimmune diseases.

Elevated hs-CRP Levels

Elevated hs-CRP - Causes

Infections: Bacterial, viral, or fungal infections can cause inflammation, raising hs-CRP levels.
Chronic inflammatory diseases: Conditions like rheumatoid arthritis, lupus, or inflammatory bowel disease (IBD) often cause elevated hs-CRP.
Cardiovascular disease: Elevated hs-CRP is associated with an increased risk of heart disease and stroke, as it reflects inflammation in the arteries.
Metabolic syndrome: A cluster of conditions, including high blood pressure, high blood sugar, excess body fat, and abnormal cholesterol levels, can raise hs-CRP.
Obesity: Excess body fat, particularly abdominal fat, is associated with chronic low-grade inflammation, leading to elevated hs-CRP.
Diabetes: Poorly controlled diabetes can increase inflammation and hs-CRP levels.
Autoimmune diseases: Lupus or rheumatoid arthritis involves chronic inflammation, which elevates hs-CRP.
Chronic infections: Periodontal disease or chronic hepatitis can cause ongoing inflammation.
Smoking: Tobacco use is linked to increased inflammation and higher hs-CRP levels.
High blood pressure: Chronic hypertension can lead to arterial inflammation and elevated hs-CRP.

Elevated hs-CRP - Symptoms

Elevated hs-CRP itself does not cause symptoms. It is a marker of underlying inflammation, so any symptoms present would be related to the condition causing the inflammation. These symptoms might include:

Fever or chills: If inflammation is due to an infection.
Fatigue: Chronic inflammation or underlying autoimmune diseases.
Pain or discomfort: Depending on the location of inflammation, such as joint pain in arthritis or chest pain in cardiovascular conditions.
Swelling or redness: In response to localized inflammation, such as an injury or skin infection.

Hormonal Health

Sex Hormone Binding Globulin (SHBG) is a glycoprotein produced mainly in the liver that binds to sex hormones, specifically testosterone and estrogen, in the bloodstream. SHBG controls the amount of testosterone and estrogen that is available for the body's tissues to use. When hormones are bound to SHBG, they are inactive and cannot be used by cells. The levels of SHBG can influence the balance of available sex hormones, affecting many bodily processes.

The Sex Hormone Binding Globulin (SHBG) test measures the level of SHBG in your blood. This test is often used to help diagnose conditions related to abnormal levels of sex hormones, such as testosterone and estrogen. It is particularly useful when total hormone levels are normal, but symptoms of hormone imbalance are present.

Low SHGB Levels

Low SHBG levels have been associated with an increased risk of developing type 2 diabetes, cardiovascular disease, and metabolic disorders including metabolic syndrome, as well as some cancers and arthritis in both genders.

Low SHBG - Causes

Obesity
Type 2 diabetes
Hypothyroidism
Cushing’s syndrome
Use of anabolic steroids or androgenic medications
Excessive androgen production (polycystic ovary syndrome (PCOS), hirsutism, hair loss, and infertility in women).
Non-alcoholic fatty liver disease (NAFLD)

Low SHBG - Symptoms

Acne
Excessive body or facial hair (hirsutism)
Oily skin
Irregular menstrual cycles (in women)
Polycystic ovary syndrome (PCOS) symptoms
Aggression or mood changes (in men)
Potential symptoms related to excess free estrogen (in women):
Weight gain
Breast tenderness
Menstrual irregularities

High SHGB Levels

Often, higher levels of SHBG are associated with positive health outcomes. For example, elevated SHBG levels have been linked to a lower risk of type 2 diabetes and prostate cancer. However, they are also linked to a higher risk of bone loss and fractures, hypogonadism in males, and hepatic cirrhosis. In some cases, it may be caused by hyperthyroidism, as thyroid hormone stimulates the production and release of SHBG.

High SHBG - Causes

Hyperthyroidism
Hypogonadism
Liver disease (Hepatic cirrhosis)
Hormones: Estrogen (including estrogen therapy or oral contraceptives), thyroid or growth hormones or other growth factors
Pregnancy
Anorexia nervosa
Aging (SHBG levels naturally increase with age)
Certain genetic conditions
Nutritional status

High SHBG - Symptoms

Decreased libido
Erectile dysfunction (in men)
Fatigue
Loss of muscle mass
Osteoporosis or decreased bone density
Mood swings or depression

Boost your efficiency

Female Comprehensive Panel

Female Comprehensive Panel

How Often You Should Get It Done

Full List of Tests in Panel

Nutrition / Metabolism

Omega

Cardiovascular Health

Hormonal Health

Complete Blood Count

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