Kidney & Urine Health focuses on how well your kidneys filter waste and excess fluids from your blood, which are then expelled through urine. Healthy kidney function is vital for maintaining a balance of electrolytes, blood pressure, and overall fluid regulation. Blood and urine tests can detect early signs of kidney dysfunction or urinary tract issues, allowing for timely intervention. Supporting kidney health through hydration, a balanced diet, and regular monitoring is essential for preventing long-term complications.
Albumin is a protein in your blood that performs essential functions, such as maintaining the balance of fluids between blood vessels and tissues. It also helps transport various substances, including hormones, vitamins, and drugs and also supports tissue growth and healing.
The serum albumin test is a valuable tool in diagnosing and managing various health conditions, including liver and kidney diseases, nutritional deficiencies, and inflammatory disorders. Regular monitoring and appropriate medical guidance are essential to address any abnormalities effectively.
Low Blood Albumin Levels (Hypoalbuminemia) - Symptoms
Symptoms of high albumin levels are generally related to the underlying cause, such as liver, kidney, or heart issues, malnutrition or malabsorption issues, chronic inflammation or infection, or burns and severe injuries. Symptoms include:
High Blood Albumin Levels (Hyperalbuminemia) - Symptoms
Symptoms of high albumin levels are generally related to the underlying cause. Symptoms include:
Microalbumin is a tiny protein produced primarily by your kidneys, which helps filter waste and excess substances from your blood. Monitoring microalbumin levels in your urine provides valuable insights into kidney health, particularly in individuals with diabetes or hypertension. Detecting microalbumin in the urine is an early indicator of kidney damage.
Low Microalbumin Levels
Low microalbumin levels are generally not concerning and suggest efficient kidney function and effective waste filtration. This is a positive sign, though some medications (e.g., ACE inhibitors or angiotensin receptor blockers), dehydration, or intense physical activity can contribute to lower levels.
High Microalbumin Levels - Causes
High microalbumin levels can indicate kidney damage or disease, such as diabetic nephropathy or hypertension-related kidney problems. Certain medications, like NSAIDs and some blood pressure drugs, can also increase microalbumin levels.
High Microalbumin Levels - Symptoms
The Albumin/Globulin Ratio is a calculated value obtained by dividing the level of albumin (a protein in the blood) by the level of globulin (another group of proteins in the blood). This ratio provides insights into various health conditions and is used for the following clinical purposes:
The urine test for Albumin/Creatinine Ratio (ACR) combines a muscle and a kidney function test. It looks at albumin, a protein that shouldn't be in your urine in large amounts if your kidneys are healthy. It also looks at creatinine, a waste product from your muscles that's normally filtered out by your kidneys.
A high ACR level can be an early sign of damage to the filtering units in your kidneys, even before you experience any symptoms. Early detection is crucial for better treatment outcomes.
This test measures the ratio of blood urea nitrogen (BUN) to creatinine in the blood. BUN comes from protein breakdown in the liver, and creatinine is a waste product from muscles. This ratio helps check kidney function.
Low BUN/Creatinine Ratio
A low Blood Urea Nitrogen (BUN) to Creatinine ratio can be caused by various factors, typically reflecting either low BUN or high creatinine. Common causes of each include:
Low BUN/Creatinine Ratio - Symptoms
Symptoms depend on the underlying cause but may include:
High BUN/Creatinine Ratio
A high Blood Urea Nitrogen (BUN) to Creatinine ratio can result from various factors, typically reflecting elevated BUN or low creatinine. Common causes of each include:
High BUN/Creatinine Ratio -Symptoms
Symptoms may start subtly and get worse as kidney function declines:
While some bacteria in the urine isn't necessarily abnormal (small amounts can be present from skin contamination during collection), a significant number of bacteria, especially with symptoms like burning urination or frequent urination, could be a sign of a urinary tract infection (UTI).
This test is a common initial screening tool to help diagnose UTIs. If bacteria are present in significant numbers along with symptoms suggestive of a UTI, further evaluation and treatment might be recommended by your doctor.
Carbon dioxide (CO2) is a colorless, odorless gas. We produce CO2 as a normal part of metabolism and eliminate it when we exhale.
A CO2 blood test, often part of an electrolyte panel, helps doctors check if your body is balancing electrolytes properly.
Your doctor might order a CO2 blood test if you have symptoms like excessive vomiting or diarrhea, fatigue, headache, trouble breathing, or weakness.
Low CO2 Levels (Hypocapnia) - Causes
Low CO2 Levels - Symptoms
High CO2 Levels (Hypercapnia) - Causes
High CO2 Levels - Symptoms
Chloride is an essential electrolyte, a negatively charged ion, found in the body. It plays a crucial role in maintaining fluid balance, forming stomach acid for digestion, and assisting in the movement of fluids in and out of cells.
Chloride measurements are used in the diagnosis and treatment of electrolyte and metabolic disorders such as cystic fibrosis and diabetic acidosis. Your healthcare provider may also order a chloride blood test if you have symptoms of an acid or fluid imbalance, including:
Low Chloride Levels (Hypochloremia) - Causes
High Chloride Levels (Hyperchloremia)- Causes
Creatinine is a waste product made by muscles during everyday activities. The kidneys filter it out of the blood and excrete it in urine. If the kidneys aren’t working well, creatinine levels in the blood increase, indicating potential kidney problems.
The serum creatinine test can provide important information about kidney function. However, normal creatinine levels don’t always mean the kidneys are healthy.
Low Creatinine Levels - Causes
Low creatinine levels in a blood test are less common, often asymptomatic, and usually not critical but can indicate certain health issues:
Low Creatinine Levels - Symptoms
Elevated Creatinine - Causes
Elevated Creatinine - General Symptoms
Elevated Creatinine - Severe Symptoms
Creatinine is a waste product of creatine. Your body uses creatine to supply your muscles with energy. As your muscles use energy, they break down. This natural breakdown of muscle tissue releases creatinine into your bloodstream.
Your kidneys typically filter creatinine. Unlike many other substances, creatinine is minimally reabsorbed by the kidneys after it is filtered, making its blood concentration a useful marker of how well the kidneys filter blood.
The creatinine level in your urine isn't a direct measurement of kidney function. However, significant changes in urinary creatinine levels can sometimes indicate potential problems with kidney function as the level normally remains stable within a certain range. A very high or low level might warrant further investigation by your doctor.
This random creatinine test measures the creatinine in your urine and is commonly used to screen for early renal disease in diabetic patients.
Abnormal creatinine levels themselves typically do not cause symptoms but may indicate underlying conditions that do, such as the following:
Low Creatinine Levels - Causes
High Creatinine Levels - Causes
Estimated Glomerular Filtration Rate (eGFR) is a measure of kidney function, estimating how much blood is filtered by the kidneys each minute. It is used to detect, evaluate, and monitor chronic kidney disease (CKD).
GFR has traditionally been estimated based on 24-hour creatinine clearance. However, a calculation of estimated GFR (eGFR) is now recommended by the National Institutes of Health (NIH) and the National Kidney Foundation. eGFR based on serum creatinine and/or cystatin C is viewed as a simpler and generally more reliable test.
Low eGFR Levels - Causes
Low eGFR Levels - General Symptoms
Low eGFR Levels - Severe Symptoms
High eGFR Levels - Causes
High eGFR Levels - Symptoms
Globulin is a group of proteins in the blood that play essential roles in fighting infections, forming blood clots, and supporting liver and kidney functions. Abnormal globulin levels can indicate various health issues, so addressing them depends on the underlying cause.
Testing globulin levels helps assess if you have the right amount to maintain health, fight infections, and transport nutrients effectively.
Low Globulin Levels (Hypoglobulinemia) - Causes
Low globulin levels can indicate gastrointestinal or liver dysfunction, renal disease, various cancers, immune deficiencies, malnutrition, severe burns, or trauma.
High Globulin Levels (Hyperglobulinemia) - Causes
Increased levels may be due to autoimmune diseases, chronic infections or inflammatory diseases, certain cancers, or liver diseases. Dehydration or pregnancy can cause temporary increases.
Abnormal Globulin Levels - Symptoms
Symptoms of abnormal globulin levels are often related to the underlying cause. Symptoms can include:
Your kidneys are like tiny factories inside your body. Their job is to clean your blood, like little filters. They take out waste products and extra water to make urine. A urine test is like checking what comes out of those factories.
One thing it tests for is tiny shapes called casts. Urinary casts may be made from white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The content of a cast can help tell your healthcare provider whether your kidney is healthy or abnormal.
Hyaline casts can be present in the urine of healthy individuals, but their presence in higher numbers may indicate an underlying issue. Normally, a small number of these casts is not a concern.
High Hyaline Casts - Causes
High Hyaline Casts - Symptoms
Hyaline casts do not cause symptoms on their own. But, they may be associated with the symptoms of the underlying condition that causes their formation. These can include:
Leukocyte esterase is an enzyme produced by white blood cells (leukocytes). It is involved in the body's defense mechanisms by helping white blood cells combat infections, especially in the urinary tract.
When the body detects an infection, white blood cells are mobilized to the site of infection. These cells release leukocyte esterase as part of their function to break down and kill bacteria and other pathogens.
Leukocyte esterase in urine is considered an indicator of a urinary tract infection (UTI). It signals that white blood cells are present and actively responding to an infection.
Leukocyte Esterase in Urine - Causes
Leukocyte Esterase in Urine - Symptoms
Your body works hard to maintain a very specific and narrow pH range in your blood (around 7.35 to 7.45) for optimal functioning of various organs and enzymes.
A urine pH test offers a snapshot of your urine's acidity or alkalinity. Doctors may recommend ongoing monitoring or additional tests to understand abnormal results. While not directly reflecting blood pH, urine pH can reveal insights regarding your metabolic health.
Acidic Urine / Low pH
Low urine pH typically does not cause symptoms but may indicate or
contribute to underlying conditions that have specific symptoms:
Neutral Urine (pH = 7.0) This is neither acidic nor alkaline and is often associated with a balanced diet and normal bodily functions.
Alkaline Urine / High pH Levels
High urine pH levels could indicate that your system is too alkaline and unable to maintain its ideal slightly alkaline state.
High pH typically does not cause symptoms but may indicate or
contribute to underlying conditions that have specific symptoms:
Potassium is a crucial mineral and electrolyte that helps your body function properly. It maintains fluid balance, controls blood pressure, sends nerve signals, helps muscles contract, supports heart function, and keeps the right balance of acids and bases in your body.
A potassium test measures the amount of potassium in your blood. Potassium levels above or below the normal range need medical attention.
Low Potassium Levels (Hypokalemia) - Causes
Low Potassium - Symptoms
Symptoms of low potassium levels include constipation, feeling weak or tired, muscle cramps, heart palpitations, tingling or numbness, and abnormal heart rhythms. In severe cases, it can cause paralysis or serious heart problems.
High Potassium Levels (Hyperkalemia) - Causes
High Potassium Levels - Symptoms
Symptoms of high potassium include chest pain, irregular heartbeats, shortness of breath, fatigue, nausea, and muscle weakness. In severe cases, it can lead to paralysis or serious heart problems.
This is a common screening test where a dipstick is dipped into your urine sample, and the presence of red blood cells is visually assessed based on a color change. It provides a semi-quantitative estimate of the number of RBCs.
The urine test for RBCs (Red Blood Cells) is like a detective looking for tiny red footprints (RBCs) at a crime scene (your urinary tract). Normally there are very few or no red blood cells in your urine. A positive urine RBC test indicates the presence of red blood cells in your urine, which could be a sign of various underlying conditions.
Urinary Red Blood Cells - Causes
Urinary Red Blood Cells - Symptoms
Specific Gravity measures the concentration of dissolved particles in urine compared to pure water. It provides insights into kidney function and hydration status.
Elevated SG levels suggest your body is struggling to maintain the right balance of water and dissolved substances, possibly indicating underlying health issues or lifestyle factors affecting kidney function.
Low Specific Gravity - Causes
Low Specific Gravity (SG) Symptoms
Elevated Specific Gravity - Causes
High Specific Gravity (SG) - Symptoms
Sodium is an important electrolyte that helps keep the right balance of fluids in your body. It also ensures that your muscles and nerves work properly.
A sodium test measures the sodium in your blood, revealing much about your health. It can show whether you drink enough water or your kidneys and heart are functioning well. Measuring sodium levels is important for diagnosing and treating several health conditions.
Low Sodium Levels (Hyponatremia) - Causes
Low Sodium Levels - Symptoms
High Sodium Levels (Hypernatremia) - Causes
High Sodium Levels - Symptoms
Proteins play vital roles in the body, including maintaining fluid balance, fighting infections, and transporting substances in the blood.
This test measures the total amount of protein in your blood, focusing on two major types: albumin and globulin. It helps assess nutritional status, diagnose kidney or liver disease, and evaluate immune system health. It can also help determine the cause of edema, a buildup of fluid that leads to swelling, typically in the ankles.
Low Blood Protein (Hypoproteinemia): Low protein levels may result from temporary conditions, like acute infections or inflammation, overhydration, overuse of diuretics, pregnancy, or severe burns. Alternatively, many chronic conditions may be the cause, such as chronic illness, congestive heart failure, liver or kidney disease, gastrointestinal disorders, malnutrition, malabsorption syndromes, medications, or genetic disorders.
Low Blood Protein Levels - Symptoms
High Blood Protein: High protein levels may indicate temporary conditions, like dehydration, or chronic issues, such as liver disease, chronic infections, certain cancers, and autoimmune diseases.
High Blood Protein Levels - Symptoms
Proteins play vital roles in the body, including maintaining fluid balance, fighting infections, and transporting substances in the blood.
The presence of protein in urine is known as proteinuria. Normally, the kidneys filter waste products from the blood while retaining essential substances like protein. If protein is found in urine, it may indicate that the kidneys are not functioning properly. This test is used to assess kidney function and to monitor chronic conditions and pregnancy.
Protein in Urine - Causes
Protein in Urine - Symptoms
Squamous epithelial cells are flat, thin cells found on the skin, the lining of the urethra (and sometimes the bladder and the ureters), and the passages of the respiratory and digestive tracts.
The test indicates if squamous epithelial cells are found in the urine. If squamous cells are present in large quantities and there are signs of infection or inflammation, it could indicate a urinary tract infection or another condition affecting the urinary tract. However, in most cases, squamous cells in a urine sample are not clinically significant and may simply indicate contamination during the sample collection.
Urinary Squamous Epithelial Cells - Causes
Urinary Squamous Epithelial Cells - Symptoms
Blood urea nitrogen, BUN, is a waste product produced when the body breaks down proteins.
The BUN test measures the amount of urea nitrogen in your bloodstream and is commonly used in the diagnosis and treatment of certain renal and metabolic diseases. This test is often used with patients who have diabetes, a family history of kidney problems, or high blood pressure.
Low Blood Urea Nitrogen: Low BUN levels aren't common. However, you may have low BUN levels from the following:
Low Blood Urea Nitrogen - General Symptoms: While individuals with low BUN are often asymptomatic, symptoms of severely low BUN are confusion, swelling, or edema. More general symptoms include:
Elevated Blood Urea Nitrogen: High BUN levels may suggest poor kidney function (chronic kidney disease, acute kidney injury, glomerulonephritis, kidney stones). However, even if your kidneys are working properly, you may have elevated BUN levels from the following:
Elevated Blood Urea Nitrogen - General Symptoms
Elevated Blood Urea Nitrogen - Severe Symptoms